SCHEMBL9516830

SCHEMBL9516830

CC(/C=C/C1(F)CC1c1cc(Cl)c(Cl)c(Cl)c1)=C\C(=O)NCC(C)C

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.34
HPGD P15428 1/20 0.32
LMNA P02545 1/20 0.31
CETP P11597 1/20 0.31
KDM4E B2RXH2 1/20 0.30
TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9515299 0.90 HPGD (0.40) EPHX2HPGDLMNAKDM4ETRPV1
SCHEMBL9516900 0.87
SCHEMBL9515734 0.82 HRH3 (0.31) EPHX2HPGDTRPV1
SCHEMBL9515730 0.78 MEN1 (0.34)
SCHEMBL9515309 0.77 HPGD (0.40) EPHX2HPGDLMNAKDM4ETRPV1
SCHEMBL9597892 0.77 HPGD (0.40) EPHX2HPGDLMNAKDM4ETRPV1
SCHEMBL9580533 0.77 HPGD (0.40) EPHX2HPGDLMNAKDM4ETRPV1
SCHEMBL9430130 0.77 HPGD (0.40) EPHX2HPGDLMNAKDM4ETRPV1
SCHEMBL9430143 0.77 HPGD (0.40) EPHX2HPGDLMNAKDM4ETRPV1
SCHEMBL9430395 0.77 HPGD (0.40) EPHX2HPGDLMNAKDM4ETRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0369762-B1 Pesticides ROUSSEL UCLAF (FR) 1993-12-29 EP claimed
US-5202356-A Insecticides, miticides THE WELLCOME FOUNDATION LIMITED (GB) 1993-04-13 US claimed
EP-0369762-A1 Pesticides ROUSSEL-UCLAF (FR) 1990-05-23 EP claimed
US-5202356-A Insecticides, miticides THE WELLCOME FOUNDATION LIMITED (GB) 1993-04-13 US disclosed
EP-0369762-A1 Pesticides ROUSSEL-UCLAF (FR) 1990-05-23 EP disclosed