SCHEMBL9580860

SCHEMBL9580860

C=CCOCC=C.CC(O)(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.44
ALDH1A1 P00352 5/20 0.41
TSHR P16473 2/20 0.41
SRC P12931 1/20 0.41
HTT P42858 1/20 0.39
CYP3A4 P08684 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
MAPT P10636 2/20 0.37
CYP2C19 P33261 1/20 0.37
HIF1A Q16665 1/20 0.37
KDM4E B2RXH2 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ELANE P08246 1/20 0.36
AKT1 P31749 2/20 0.36
GAA P10253 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8723027 0.82 ALDH1A1 (0.47) CES1ALDH1A1TSHRSRCHTT
SCHEMBL9810428 0.82 ALDH1A1 (0.41) CES1ALDH1A1TSHRSRCHTT
SCHEMBL10398398 0.82 ALDH1A1 (0.47) CES1ALDH1A1TSHRSRCHTT
SCHEMBL58021 0.82 CES1 (0.55) CES1ALDH1A1TSHRSRCCYP3A4
Ether SCHEMBL5570218 0.81 CES1 (0.49) CES1ALDH1A1TSHRSRCL3MBTL1
Methoxymethane SCHEMBL7788767 0.81 CES1 (0.59) CES1ALDH1A1TSHRSRCL3MBTL1
SCHEMBL9718678 0.81 ALDH1A1 (0.41) CES1ALDH1A1TSHRSRCHTT
SCHEMBL11594361 0.79 ALDH1A1 (0.38) CES1ALDH1A1TSHRSRCHTT
SCHEMBL11878913 0.79 SCN5A (0.40) CES1ALDH1A1TSHRSRCHTT
SCHEMBL25375795 0.78 CES1 (0.45) CES1ALDH1A1TSHRSRCHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5176985-A REACTION PRODUCT, PREPARATION THEREOF AND RADIATION-SENSITIVE MATERIAL OBTAINED THEREWITH BASF AKTIENGESELLSCHAFT (DE) 1993-01-05 US disclosed
US-3937722-A PHOTOSENSITIZERS, IRRADIATION POLYMERIZATION, CROSSLINKING BAYER AG (DT) 1976-02-10 US disclosed