Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 5/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.46 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.46 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.46 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.46 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4324691 | 0.91 | HSD17B2 (0.47) | HSD17B2HSD17B1MTNR1AMTNR1BMAOB | |
| SCHEMBL12463079 | 0.91 | HSD17B2 (0.47) | HSD17B2HSD17B1MTNR1AMTNR1BMAOB | |
| SCHEMBL3442214 | 0.91 | HSD17B2 (0.47) | HSD17B2HSD17B1MTNR1AMTNR1BMAOB | |
| SCHEMBL9763422 | 0.91 | HSD17B2 (0.47) | HSD17B2HSD17B1MTNR1AMTNR1BMAOB | |
| SCHEMBL17372968 | 0.91 | HSD17B2 (0.47) | HSD17B2HSD17B1MTNR1AMTNR1BMAOB | |
| SCHEMBL13136850 | 0.91 | HSD17B2 (0.47) | HSD17B2HSD17B1MTNR1AMTNR1BMAOB | |
| SCHEMBL9581154 | 0.91 | ALKBH3 (0.48) | HSD17B2HSD17B1MTNR1AMTNR1BMEN1 | |
| SCHEMBL12048180 | 0.89 | MTNR1A (0.51) | HSD17B2HSD17B1MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL12047889 | 0.89 | MTNR1A (0.51) | HSD17B2HSD17B1MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL915801 | 0.89 | CA4 (0.45) | HSD17B2HSD17B1MTNR1AMTNR1BMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227449-A | Polydiphenylsiloxane-Carbonate Block Polymers | XEROX CORPORATION (US) | 1993-07-13 | — | — | US | disclosed |
| US-5215844-A | Photoconductive imaging members with polyhydroxy ether binders | XEROX CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| US-5166021-A | Multilayer imaging member with charge generating and charge transport layers | XEROX CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| US-5162485-A | Binders in charge transport or charge generation layers | XEROX CORPORATION (US) | 1992-11-10 | — | — | US | disclosed |
| US-5080987-A | Photoconductive imaging members with polycarbonate binders | XEROX CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |
| US-5011906-A | Photoconductive imaging members with N,N-bis(biarylyl)aniline charge transport polymers | XEROX CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| US-5008169-A | Photoconductive imaging members with polyphosphazenes | XEROX CORPORATION (US) | 1991-04-16 | — | — | US | disclosed |
| US-5004663-A | Photoconductive imaging members with polyphosphazene binders | XEROX CORPORATION (US) | 1991-04-02 | — | — | US | disclosed |
| US-4959288-A | Photoconductive imaging members with diaryl biarylylamine copolymer charge transport layers | XEROX CORPORATION (US) | 1990-09-25 | — | — | US | disclosed |
| US-4946754-A | Photoconductive imaging members with diaryl biarylylamine charge transporting components | XEROX CORPORATION (US) | 1990-08-07 | — | — | US | disclosed |
| US-4937165-A | Photoconductive imaging members with N,N-bis(biarylyl)aniline charge transport polymers | XEROX CORPORATION (US) | 1990-06-26 | — | — | US | disclosed |