SCHEMBL958137

SCHEMBL958137

Oc1ccc2c(c1O)-c1ccccc1C=CN=N2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.37
MAPT P10636 3/20 0.37
MAOA P21397 3/20 0.37
KMT2A Q03164 3/20 0.37
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 2/20 0.37
CYP3A4 P08684 2/20 0.37
HPGD P15428 2/20 0.37
ALOX15 P16050 2/20 0.37
ALOX12 P18054 2/20 0.37
MAPK1 P28482 2/20 0.37
RECQL P46063 2/20 0.37
DAPK1 P53355 2/20 0.37
CYP1B1 Q16678 2/20 0.37
HSD17B10 Q99714 2/20 0.37
BCL2 P10415 1/20 0.37
APEX1 P27695 1/20 0.37
MCL1 Q07820 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ABCG2 Q9UNQ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL955074 0.75
SCHEMBL5056850 0.75
SCHEMBL160698 0.72 ALDH1A1 (0.33) MEN1MAPTKMT2AKDM4EALDH1A1
SCHEMBL160697 0.72 ALDH1A1 (0.33) MEN1MAPTKMT2AKDM4EALDH1A1
SCHEMBL5052532 0.72 NPC1 (0.30) HPGDSMN1; SMN2
SCHEMBL476897 0.59 MEN1 (0.57) MEN1MAPTMAOAKMT2AKDM4E
SCHEMBL31185666 0.59 MEN1 (0.57) MEN1MAPTMAOAKMT2AKDM4E
SCHEMBL30026063 0.59 HPGD (0.52) MEN1MAPTMAOAKMT2AKDM4E
SCHEMBL1151769 0.59 HPGD (0.52) MEN1MAPTMAOAKMT2AKDM4E
SCHEMBL7593039 0.59 SETD7 (0.33) MEN1MAPTKMT2AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2242789-B1 COPOLYMERS OF DIBENZODIAZOCINE WITH DIFUNCTIONAL MONOMERS CONTAINING SULFONE AND/OR KETONE UNITS SOLVAY SPECIALTY POLYMERS USA (US) 2017-05-24 EP disclosed
US-8420750-B2 Copolymers of dibendiazocine with difunctional monomers containing sulfone and/or ketone units SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2013-04-16 US disclosed
US-20110009563-A1 Copolymers of dibendiazocine with difunctional monomers containing sulfone and/or ketone units SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-01-13 US disclosed
EP-2242789-A1 COPOLYMERS OF DIBENZODIAZOCINE WITH DIFUNCTIONAL MONOMERS CONTAINING SULFONE AND/OR KETONE UNITS Solvay Advanced Polymers, L.L.C. (US) 2010-10-27 EP disclosed
WO-2009101064-A1 COPOLYMERS OF DIBENZODIAZOCINE WITH DIFUNCTIONAL MONOMERS CONTAINING SULFONE AND/OR KETONE UNITS SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2009-08-20 WO disclosed