⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL215646 | 0.78 | — | — | |
| SCHEMBL18654173 | 0.78 | — | — | |
| SCHEMBL24113 | 0.76 | — | — | |
| SCHEMBL9021390 | 0.76 | — | — | |
| SCHEMBL3226988 | 0.76 | — | — | |
| SCHEMBL5051122 | 0.76 | LMNA (0.46) | — | |
| Hydrochloric Acid SCHEMBL529345 | 0.73 | — | — | |
| SCHEMBL647006 | 0.73 | — | — | |
| SCHEMBL901230 | 0.73 | TP53 (0.57) | — | |
| Acetone SCHEMBL22720597 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148537-B2 | Substituted acetophenones useful as PDE4 inhibitors | LEO PHARMA A/S (DK) | 2012-04-03 | — | — | US | claimed |
| EP-2125736-B1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA AS (DK) | 2011-03-30 | — | — | EP | claimed |
| US-20100035908-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA (DK) | 2010-02-11 | — | — | US | claimed |
| EP-2125736-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | Leo Pharma A/S (DK) | 2009-12-02 | — | — | EP | claimed |
| WO-2008077404-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA A/S (DK) | 2008-07-03 | — | — | WO | claimed |
| EP-0094641-B1 | DIPHENYL SULFONE COMPOUNDS, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-09-10 | — | — | EP | claimed |
| US-4565569-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-01-21 | — | — | US | claimed |
| US-4545812-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-10-08 | — | — | US | claimed |
| EP-0094641-A2 | Diphenyl sulfone compounds, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-11-23 | — | — | EP | claimed |
| JP-9053094-A | — | — | None | — | — | JP | disclosed |
| CN-105830270-A | Nonaqueous electrolyte, electrical storage device using same, and carboxylic acid ester compound used in same | 宇部兴产株式会社 | 2016-08-03 | — | — | CN | disclosed |
| US-9089139-B2 | Agri-horticultural pest control compositions comprising 4-(3-butynyl)aminopyrimidine derivatives | SDS BIOTECH K. K. (JP) | 2015-07-28 | — | — | US | disclosed |
| EP-2455371-B1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | SDS BIOTECH CORP (JP) | 2013-12-25 | — | — | EP | disclosed |
| EP-2664238-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVE-CONTAINING PEST CONTROL COMPOSITION FOR AGRICULTURAL OR HORTICULTURAL USE | SDS Biotech K. K. (JP) | 2013-11-20 | — | — | EP | disclosed |
| EP-0094641-A2 | Diphenyl sulfone compounds, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-11-23 | — | — | EP | disclosed |
| US-4415354-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | ROHM AND HAAS COMPANY (US) | 1983-11-15 | — | — | US | disclosed |
| US-4366316-A | FROM OXAZOLINOAZETIDINONE AND ACID | SHIONOGI & CO., LTD. (JP) | 1982-12-28 | — | — | US | disclosed |
| US-4330324-A | PREEMERGENCE APPLICATION | ROHM AND HAAS COMPANY (US) | 1982-05-18 | — | — | US | disclosed |
| US-4220468-A | Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1980-09-02 | — | — | US | disclosed |
| US-4093446-A | Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1978-06-06 | — | — | US | disclosed |