Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 16/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9581775 | 1.00 | IDO1 (0.37) | IDO1ABCB1LTB4RLTB4R2HPGD | |
| SCHEMBL9581769 | 1.00 | IDO1 (0.37) | IDO1ABCB1LTB4RLTB4R2HPGD | |
| SCHEMBL9789591 | 0.88 | LTB4R (0.39) | IDO1ABCB1LTB4RLTB4R2HPGD | |
| SCHEMBL9789590 | 0.88 | LTB4R (0.39) | IDO1ABCB1LTB4RLTB4R2HPGD | |
| SCHEMBL9789592 | 0.88 | LTB4R (0.39) | IDO1ABCB1LTB4RLTB4R2HPGD | |
| SCHEMBL5868357 | 0.79 | IDO1 (0.40) | IDO1ABCB1 | |
| SCHEMBL5868353 | 0.79 | IDO1 (0.40) | IDO1ABCB1 | |
| SCHEMBL6274078 | 0.79 | IDO1 (0.40) | IDO1ABCB1 | |
| SCHEMBL8947007 | 0.78 | IDO1 (0.36) | IDO1ABCB1 | |
| SCHEMBL8947011 | 0.78 | IDO1 (0.36) | IDO1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210234-A | Benzopyran intermediates | BEECHAM GROUP P.L.C. (GB) | 1993-05-11 | — | — | US | disclosed |
| EP-0250077-B1 | PHARMACOLOGICALLY ACTIVE BENZOPYRANES | BEECHAM GROUP PLC (GB) | 1992-01-02 | — | — | EP | disclosed |
| US-5075460-A | Hypotensive agents | BEECHAM GROUP PLC (GB) | 1991-12-24 | — | — | US | disclosed |
| US-4943582-A | Active compounds | BEECHAM GROUP P.L.C. (GB) | 1990-07-24 | — | — | US | disclosed |
| EP-0250077-A2 | Pharmacologically active benzopyranes | BEECHAM GROUP PLC (GB) | 1987-12-23 | — | — | EP | disclosed |