Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 6/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 7/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 7/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9581839 | 1.00 | KCNA5 (0.39) | KCNA5KCNE1KCNQ1IDO1ABCB1 | |
| SCHEMBL9581830 | 1.00 | KCNA5 (0.39) | KCNA5KCNE1KCNQ1IDO1ABCB1 | |
| SCHEMBL9197778 | 0.80 | IDO1 (0.39) | KCNA5KCNE1KCNQ1IDO1ABCB1 | |
| SCHEMBL9197769 | 0.80 | IDO1 (0.39) | KCNA5KCNE1KCNQ1IDO1ABCB1 | |
| SCHEMBL9146935 | 0.80 | IDO1 (0.39) | KCNA5KCNE1KCNQ1IDO1ABCB1 | |
| SCHEMBL7474225 | 0.79 | KCNA5 (0.41) | KCNA5KCNE1KCNQ1ABCB1MEN1 | |
| SCHEMBL7474233 | 0.79 | KCNA5 (0.41) | KCNA5KCNE1KCNQ1ABCB1MEN1 | |
| SCHEMBL7474229 | 0.79 | KCNA5 (0.41) | KCNA5KCNE1KCNQ1ABCB1MEN1 | |
| SCHEMBL8946876 | 0.78 | IDO1 (0.38) | KCNE1KCNQ1IDO1ABCB1MEN1 | |
| SCHEMBL8794829 | 0.78 | IDO1 (0.38) | KCNE1KCNQ1IDO1ABCB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210234-A | Benzopyran intermediates | BEECHAM GROUP P.L.C. (GB) | 1993-05-11 | — | — | US | claimed |
| US-5210234-A | Benzopyran intermediates | BEECHAM GROUP P.L.C. (GB) | 1993-05-11 | — | — | US | disclosed |
| EP-0250077-B1 | PHARMACOLOGICALLY ACTIVE BENZOPYRANES | BEECHAM GROUP PLC (GB) | 1992-01-02 | — | — | EP | disclosed |
| US-5075460-A | Hypotensive agents | BEECHAM GROUP PLC (GB) | 1991-12-24 | — | — | US | disclosed |
| US-4943582-A | Active compounds | BEECHAM GROUP P.L.C. (GB) | 1990-07-24 | — | — | US | disclosed |