SCHEMBL9582971

SCHEMBL9582971

Cc1[nH]cnc1C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HRH2 P25021 1/20 0.34
HRH1 P35367 1/20 0.34
HRH4 Q9H3N8 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
GABRR1 P24046 1/20 0.32
HPGD P15428 1/20 0.32
FDPS P14324 1/20 0.32
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9584344 0.89 HRH2 (0.35) HRH2HRH1HRH4HRH3TDP1
SCHEMBL9662195 0.83 HPGD (0.36) HRH2HRH1HRH4HRH3TDP1
SCHEMBL9582663 0.80 HRH2 (0.38) HRH2HRH1HRH4HRH3TDP1
SCHEMBL9582927 0.73 HRH2 (0.33) HRH2HRH1HRH4HRH3TDP1
SCHEMBL9582765 0.73 HPGD (0.50) HRH2HRH1HRH4HRH3TDP1
SCHEMBL9581310 0.67 HPGD (0.44) HPGD
SCHEMBL12778268 0.64 HRH2 (0.35) HRH2HRH1HRH4HRH3TDP1
SCHEMBL12778264 0.62
SCHEMBL2873975 0.61 KDM4E (0.43) KDM4EPOLBMAPTKMT2A
SCHEMBL9582021 0.61 HPGD (0.47) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5252590-A Insecticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-10-12 US disclosed
EP-0520824-A1 1-pyridylimidazole derivatives and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-12-30 EP disclosed