Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584344 | 0.85 | HRH2 (0.35) | HPGDHRH2HRH1HRH4HRH3 | |
| SCHEMBL9582971 | 0.83 | HRH2 (0.34) | HPGDHRH2HRH1HRH4HRH3 | |
| SCHEMBL9582663 | 0.80 | HRH2 (0.38) | HPGDHRH2HRH1HRH4HRH3 | |
| SCHEMBL9582927 | 0.73 | HRH2 (0.33) | HPGDHRH2HRH1HRH4HRH3 | |
| SCHEMBL9582765 | 0.73 | HPGD (0.50) | HPGDHRH2HRH1HRH4HRH3 | |
| SCHEMBL12778268 | 0.64 | HRH2 (0.35) | HRH2HRH1HRH4HRH3TDP1 | |
| SCHEMBL9581310 | 0.63 | HPGD (0.44) | HPGD | |
| SCHEMBL12778264 | 0.62 | — | — | |
| SCHEMBL31710542 | 0.62 | HPGD (0.39) | HPGD | |
| SCHEMBL677524 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520824-A1 | 1-pyridylimidazole derivatives and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-12-30 | — | — | EP | disclosed |