Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | AHCY | P23526 | 7/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584645 | 0.86 | EP300 (0.52) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL9584354 | 0.86 | EP300 (0.52) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL9583391 | 0.82 | FGFR1 (0.52) | ADORA2AEP300ALDH1A1CYP3A4ADCY5 | |
| SCHEMBL9583148 | 0.81 | PDE3A (0.60) | ALDH1A1CYP3A4 | |
| SCHEMBL10813839 | 0.80 | ADORA2A (0.50) | ADORA2AADORA1ADORA2BAHCYPI4KA | |
| SCHEMBL9583892 | 0.80 | ADORA2A (0.53) | ADORA2AADORA1ADORA2BAHCYPI4KA | |
| SCHEMBL10817453 | 0.79 | ADORA2A (0.51) | ADORA2AADORA1ADORA2BAHCYPI4KA | |
| SCHEMBL9582655 | 0.78 | PDE3A (0.67) | ALDH1A1CYP3A4 | |
| SCHEMBL10818140 | 0.76 | ADORA2A (0.50) | ADORA2AADORA1AHCYPI4KAPI4K2B | |
| SCHEMBL9583786 | 0.74 | P2RY1 (0.48) | ADORA2AADORA1EP300ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250535-A | Herpes virus; nontoxic; side effect reduction; humans and veterinary medicine | SYNTEX INC. (US) | 1993-10-05 | — | — | US | disclosed |
| US-4803271-A | Process for preparing guanine derivatives | SYNTEX (U.S.A.) INC. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4612314-A | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1986-09-16 | — | — | US | disclosed |
| EP-0085424-A2 | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl)purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1983-08-10 | — | — | EP | disclosed |