Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | PI4KA | P42356 | 2/20 | 0.49 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.49 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.49 |
| ▸ | ADCY5 | O95622 | 5/20 | 0.47 |
| ▸ | FAP | Q12884 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | AHCY | P23526 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10818140 | 0.94 | ADORA2A (0.50) | ADORA2AADORA1ALDH1A1CYP3A4PI4KA | |
| SCHEMBL9583892 | 0.88 | ADORA2A (0.53) | ADORA2AADORA1ALDH1A1CYP3A4PI4KA | |
| SCHEMBL10817453 | 0.87 | ADORA2A (0.51) | ADORA2AADORA1ALDH1A1CYP3A4PI4KA | |
| SCHEMBL9584354 | 0.82 | EP300 (0.52) | ADORA2AADORA1ALDH1A1CYP3A4PI4KA | |
| SCHEMBL9584645 | 0.82 | EP300 (0.52) | ADORA2AADORA1ALDH1A1CYP3A4PI4KA | |
| SCHEMBL8846475 | 0.82 | ADORA2A (0.56) | ADORA2AADORA1ALDH1A1CYP3A4PI4KA | |
| SCHEMBL9583606 | 0.80 | ADORA2A (0.45) | ADORA2AADORA1ALDH1A1CYP3A4PI4KA | |
| SCHEMBL30292318 | 0.80 | ADORA2A (0.64) | ADORA2AADORA1ALDH1A1CYP3A4PI4KA | |
| SCHEMBL4093935 | 0.80 | ADORA2A (0.64) | ADORA2AADORA1ALDH1A1CYP3A4PI4KA | |
| SCHEMBL17758843 | 0.78 | ENPP1 (0.48) | ADORA2AADORA1CYP3A4PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105135-B1 | SUBSTITUTED 9-(1-0- OR 3-0-MONOSUBSTITUTED OR 1,3-DI-0-SUBSTITUTED 1,3 DIHYDROXY-2-PROPOXYMETHYL) PURINES AS ANTIVIRAL AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-03-18 | — | — | EP | claimed |
| EP-0105135-A1 | Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-di-0-substituted 1,3 dihydroxy-2-propoxymethyl) purines as antiviral agents | SYNTEX (U.S.A.) INC. (US) | 1984-04-11 | — | — | EP | claimed |