Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | VCP | P55072 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 3/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.43 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9583542 | 0.86 | MEN1 (0.51) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9583532 | 0.83 | PDE3A (0.47) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9583855 | 0.83 | MEN1 (0.48) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9123481 | 0.83 | BLM (0.62) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9582822 | 0.82 | PDE3A (0.44) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| Ammonia Solution, Strong SCHEMBL10907047 | 0.82 | BLM (0.60) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL10638325 | 0.81 | LMNA (0.59) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL10818089 | 0.81 | PDE3A (0.41) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9582915 | 0.81 | MEN1 (0.56) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL10904901 | 0.80 | CCNE1 (0.56) | BLMMEN1ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250535-A | Herpes virus; nontoxic; side effect reduction; humans and veterinary medicine | SYNTEX INC. (US) | 1993-10-05 | — | — | US | disclosed |
| US-4803271-A | Process for preparing guanine derivatives | SYNTEX (U.S.A.) INC. (US) | 1989-02-07 | — | — | US | disclosed |
| EP-0105135-B1 | SUBSTITUTED 9-(1-0- OR 3-0-MONOSUBSTITUTED OR 1,3-DI-0-SUBSTITUTED 1,3 DIHYDROXY-2-PROPOXYMETHYL) PURINES AS ANTIVIRAL AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-03-18 | — | — | EP | disclosed |
| US-4612314-A | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1986-09-16 | — | — | US | disclosed |
| US-4609661-A | HERPES VIRUS | SYNTEX (U.S.A.) INC. (US) | 1986-09-02 | — | — | US | disclosed |
| US-4556659-A | Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-Di-0-substituted propoxymethyl)-purines as antiviral agents | SYNTEX (U.S.A.) INC. (US) | 1985-12-03 | — | — | US | disclosed |
| EP-0105135-A1 | Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-di-0-substituted 1,3 dihydroxy-2-propoxymethyl) purines as antiviral agents | SYNTEX (U.S.A.) INC. (US) | 1984-04-11 | — | — | EP | disclosed |
| EP-0085424-A2 | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl)purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1983-08-10 | — | — | EP | disclosed |