Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 4/20 | 0.53 |
| ▸ | CPT1B | Q92523 | 4/20 | 0.53 |
| ▸ | CPT2 | P23786 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.36 |
| ▸ | GSK3B | P49841 | 6/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CLK3 | P49761 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL957856 | 0.83 | CPT1A (0.75) | CPT1ACPT1BCPT2KMT2AAGTR1 | |
| SCHEMBL958457 | 0.80 | CPT1A (0.47) | CPT1ACPT1BCPT2KMT2ASMN1; SMN2 | |
| SCHEMBL957884 | 0.78 | CPT1A (0.55) | CPT1ACPT1BCPT2USP2PTGER4 | |
| SCHEMBL959272 | 0.77 | CPT1A (0.41) | CPT1ACPT1BCPT2PTGER4RORC | |
| SCHEMBL958064 | 0.76 | CPT1A (0.75) | CPT1ACPT1BCPT2PTGER4 | |
| SCHEMBL960086 | 0.69 | CPT1A (0.70) | CPT1ACPT1BCPT2KMT2AAGTR1 | |
| SCHEMBL958455 | 0.66 | CPT1A (0.44) | CPT1ACPT1BCPT2SMN1; SMN2PTGER4 | |
| SCHEMBL957678 | 0.65 | CPT1A (0.51) | CPT1ACPT1BKMT2AMEN1RAB9A | |
| SCHEMBL28803661 | 0.64 | XDH (0.66) | KMT2AMEN1RAB9AUSP2SMN1; SMN2 | |
| SCHEMBL961810 | 0.63 | PTGER4 (0.61) | CPT1ACPT1BKMT2AMEN1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015234-A1 | INDAZOLE DERIVATIVES | ACKERMANN JEAN | 2011-01-20 | — | — | US | claimed |
| US-20110015234-A1 | INDAZOLE DERIVATIVES | ACKERMANN JEAN | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015234-A1 | INDAZOLE DERIVATIVES | CPT1A, CPT1B, CES1 | CPT1A 1/4885CPT1B 2/4885CPT2 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.