Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 3/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.33 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.33 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10815175 | 0.89 | PDE3A (0.35) | ALDH1A1LMNAPDE3ACYP1A2TSHR | |
| SCHEMBL9583247 | 0.88 | CYP2C19 (0.43) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL9583975 | 0.88 | CYP2C19 (0.43) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL9584601 | 0.88 | CYP2C19 (0.43) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL10813165 | 0.85 | PDE3A (0.41) | ALDH1A1LMNAPDE3ACYP1A2TSHR | |
| SCHEMBL9584012 | 0.84 | CYP1A2 (0.52) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL9584085 | 0.82 | TLR2 (0.34) | — | |
| SCHEMBL9583322 | 0.82 | PDE3A (0.41) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL9583455 | 0.82 | ALDH1A1 (0.40) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL10816124 | 0.80 | PDE3A (0.36) | ALDH1A1LMNAPDE3ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250535-A | Herpes virus; nontoxic; side effect reduction; humans and veterinary medicine | SYNTEX INC. (US) | 1993-10-05 | — | — | US | disclosed |
| US-4803271-A | Process for preparing guanine derivatives | SYNTEX (U.S.A.) INC. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4612314-A | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1986-09-16 | — | — | US | disclosed |