Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586913 | 0.94 | CYP2D6 (0.39) | ADORA2AADORA2BADORA3ADORA1MEN1 | |
| SCHEMBL9585125 | 0.73 | DPP4 (0.38) | MEN1KMT2ADPP4TSHRLMNA | |
| SCHEMBL9585449 | 0.68 | PDE4A (0.44) | MEN1KMT2ATSHRLMNACYP1A2 | |
| SCHEMBL9585563 | 0.68 | ADORA3 (0.45) | ADORA3MEN1KMT2AMAPTDPP4 | |
| SCHEMBL9586302 | 0.65 | ADORA3 (0.44) | ADORA2AADORA2BADORA3ADORA1MEN1 | |
| SCHEMBL9584784 | 0.63 | CYP2D6 (0.48) | ADORA3MEN1KMT2AMAPTDPP4 | |
| SCHEMBL9584780 | 0.63 | CYP2D6 (0.48) | ADORA3MEN1KMT2AMAPTDPP4 | |
| SCHEMBL9585337 | 0.63 | ADORA2A (0.48) | ADORA2AADORA2BADORA3ADORA1MEN1 | |
| SCHEMBL9585798 | 0.62 | CYP2D6 (0.50) | MEN1KMT2ATSHRLMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL5229896 | 0.61 | ADORA2A (0.46) | ADORA2AADORA2BADORA3ADORA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270316-A | Condensed purine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0423805-A2 | Condensed purine derivatives | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1991-04-24 | — | — | EP | disclosed |