SCHEMBL9585255

SCHEMBL9585255

C=Cc1cc(N=C=O)cc(N=C=O)c1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYP3A4 P08684 2/20 0.35
TSHR P16473 1/20 0.35
TRPA1 O75762 1/20 0.35
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17263541 0.81 MAPK1 (0.40) MAPK1TDP1CYP3A4TSHRTRPA1
SCHEMBL131042 0.80 TDP1 (0.50) MAPK1TDP1CYP3A4TSHRTRPA1
SCHEMBL3626567 0.79 TDP1 (0.44) MAPK1TDP1CYP3A4TSHRTRPA1
SCHEMBL325040 0.77 CYP3A4 (0.50) MAPK1TDP1CYP3A4TSHRTRPA1
SCHEMBL17263542 0.72 CYP3A4 (0.45) MAPK1TDP1CYP3A4TSHRTRPA1
SCHEMBL9586008 0.70 CYP3A4 (0.37) MAPK1TDP1CYP3A4TSHRTRPA1
SCHEMBL109084 0.69 CYP3A4 (0.48) MAPK1TDP1CYP3A4TSHRTRPA1
SCHEMBL19344708 0.69 MAPK1 (0.41) MAPK1TDP1CYP3A4TSHRTRPA1
SCHEMBL13384704 0.69 MAPK1 (0.41) MAPK1TDP1CYP3A4TSHRTRPA1
SCHEMBL28497381 0.69 MAPK1 (0.41) MAPK1TDP1CYP3A4TSHRTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5213934-A Core of colorant and binder grafted to polymeric shell XEROX CORPORATION (US) 1993-05-25 US claimed
US-5213934-A Core of colorant and binder grafted to polymeric shell XEROX CORPORATION (US) 1993-05-25 US disclosed