SCHEMBL3626567

SCHEMBL3626567

C=Cc1cccc(N=C=O)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.44
TP53 P04637 1/20 0.44
MAPK1 P28482 1/20 0.41
CYP3A4 P08684 3/20 0.39
TRPA1 O75762 1/20 0.39
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
PTGS2 P35354 1/20 0.33
JAK2 O60674 1/20 0.31
S1PR4 O95977 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29952896 0.84 ALDH1A1 (0.47) TDP1MAPK1CYP3A4TRPA1ALDH1A1
SCHEMBL11658736 0.81 MIF (0.48) TDP1TP53CYP3A4ALDH1A1TSHR
SCHEMBL27322677 0.81 CYP3A4 (0.43) TDP1MAPK1CYP3A4TRPA1ALDH1A1
SCHEMBL125648 0.81 MAPK1 (0.41) TDP1MAPK1CYP3A4TRPA1ALDH1A1
SCHEMBL9585255 0.79 MAPK1 (0.38) TDP1MAPK1CYP3A4TRPA1ALDH1A1
SCHEMBL30657694 0.79 NFE2L2 (0.46) TDP1MAPK1CYP3A4TRPA1ALDH1A1
Ethylene SCHEMBL10425506 0.79 TDP1 (0.50) TDP1MAPK1CYP3A4TRPA1ALDH1A1
SCHEMBL10615043 0.79 TDP1 (0.54) TDP1MAPK1CYP3A4TRPA1ALDH1A1
SCHEMBL27873 0.79 TDP1 (0.54) TDP1MAPK1CYP3A4TRPA1ALDH1A1
SCHEMBL28420288 0.78 CYP3A4 (0.41) TDP1MAPK1CYP3A4TRPA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5213934-A Core of colorant and binder grafted to polymeric shell XEROX CORPORATION (US) 1993-05-25 US claimed
US-12037463-B2 Antimicrobial ophthalmic devices comprising polysiloxane-polyglycerol block copolymers and methods of making and use thereof Clearlab Sg Pte Ltd. (SG) 2024-07-16 US disclosed
US-12037463-B2 Antimicrobial ophthalmic devices comprising polysiloxane-polyglycerol block copolymers and methods of making and use thereof Clearlab Sg Pte Ltd. (SG) 2024-07-16 US disclosed
US-20230227613-A1 ANTIMICROBIAL OPHTHALMIC DEVICES COMPRISING POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF CLEARLAB SG PTE LTD (SG) 2023-07-20 US disclosed
US-20230227613-A1 ANTIMICROBIAL OPHTHALMIC DEVICES COMPRISING POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF CLEARLAB SG PTE LTD (SG) 2023-07-20 US disclosed
US-11649325-B2 Actinically-crosslinkable polysiloxane-polyglycerol block copolymers and methods of making and use thereof Clearlab Sg Pte Ltd. (SG) 2023-05-16 US disclosed
US-20210246270-A1 ACTINICALLY-CROSSLINKABLE POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF Clearlab Sg Pte Ltd. (SG) 2021-08-12 US disclosed
WO-2021049278-A1 ADDITION-CURABLE LIQUID SILICONE RUBBER COMPOSITION FOR AIRBAGS, AND AIRBAG 信越化学工業株式会社 2021-03-18 WO disclosed
CN-1537876-B Multi-branch polymer, its production method and its application MITSU CHEMICALS INC 2013-01-16 CN disclosed
US-7795347-B2 Multi-branched polymer, process for producing the same, and applications thereof MITSUI CHEMICALS, INC. (JP) 2010-09-14 US disclosed
CN-1537876-A Multi-branch polymer, its production method and its application ������ѧ��ʽ���� 2004-10-20 CN disclosed
EP-1457512-A1 Multi-branched polymer, process for producing the same, and applications thereof Mitsui Chemicals, Inc. (JP) 2004-09-15 EP disclosed
EP-1396504-A2 Polyolefin macromonomer, graft polymer obtained from the polyolefin macromonomer, and use thereof Mitsui Chemicals, Inc. (JP) 2004-03-10 EP disclosed
EP-0844186-A1 Package for reactive hot-melt adhesive Ato Findley S.A. (FR) 1998-05-27 EP disclosed
EP-0661221-A1 Liner packaging for reactive hot melt adhesive National Starch and Chemical Investment Holding Corporation (US) 1995-07-05 EP disclosed
US-5318198-A Hot melt adhesive container for use with heated platen dispensing equipment H.B. FULLER LICENSING & FINANCING INC. (US) 1994-06-07 US disclosed
EP-0555406-A1 HEATED PLATEN DISPENSING EQUIPMENT AND METHOD H.B. FULLER LICENSING & FINANCING, INC. (US) 1993-08-18 EP disclosed
US-5213934-A Core of colorant and binder grafted to polymeric shell XEROX CORPORATION (US) 1993-05-25 US disclosed
US-5143255-A Dispensing urethane by delidding isocyanate adhesive container and contacting hot platen with hot melt adhesive, dispensing hot melt through heated platen, removing second lid, sealing open end to open second container with hinged collar H. B. FULLER COMPANY (US) 1992-09-01 US disclosed
WO-1992007663-A1 CONTAINER USED WITH HEATED PLATEN DISPENSING EQUIPMENT H.B. FULLER LICENSING & FINANCING INC. (US) 1992-05-14 WO disclosed