Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9585161 | 0.85 | EDNRA (0.36) | KDM4EL3MBTL1 | |
| SCHEMBL9585466 | 0.85 | KDM4E (0.31) | KDM4EL3MBTL1 | |
| SCHEMBL9586209 | 0.81 | BAZ2B (0.45) | KDM4EPOLB | |
| SCHEMBL9584755 | 0.81 | — | — | |
| SCHEMBL9585087 | 0.80 | TRPA1 (0.35) | TRPA1 | |
| SCHEMBL9585132 | 0.77 | KDM4E (0.37) | KDM4EPOLBL3MBTL1 | |
| SCHEMBL9585030 | 0.77 | MAPT (0.40) | KDM4EPOLB | |
| SCHEMBL9585206 | 0.77 | HPGD (0.35) | KDM4EPOLB | |
| SCHEMBL9583759 | 0.76 | POLB (0.49) | KDM4EPOLBL3MBTL1 | |
| SCHEMBL9584539 | 0.75 | NPC1 (0.41) | KDM4EPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5240947-A | Thrombocyte aggregation inhibitors, antiallergens | NATIONAL SCIENCE COUNCIL (TW) | 1993-08-31 | — | — | US | disclosed |