Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 5/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997862 | 0.91 | KCNH2 (0.54) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL7997865 | 0.91 | KCNH2 (0.54) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL10378233 | 0.86 | KCNH2 (0.48) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL5508837 | 0.82 | KCNH2 (0.64) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL30181127 | 0.82 | KCNH2 (0.64) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL13789926 | 0.81 | KCNH2 (0.63) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL8102541 | 0.81 | KCNH2 (0.72) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL8118056 | 0.81 | KCNH2 (0.72) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL10586593 | 0.80 | KCNH2 (0.81) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL10586588 | 0.80 | KCNH2 (0.81) | KCNH2HRH3ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252734-A | Antibacterial 5-alkylquinolonecarboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1993-10-12 | — | — | US | disclosed |
| US-5140033-A | For prevention or treatment of bacterial infections in humans or animals | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-18 | — | — | US | disclosed |