Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 3/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9585476 | 0.86 | KCNH2 (0.64) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL7498379 | 0.83 | KCNH2 (0.46) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL10646730 | 0.83 | KDM4E (0.49) | HRH3ALDH1A1KDM4ELMNAHPGD | |
| Hydrochloric Acid SCHEMBL9669818 | 0.82 | KDM4E (0.48) | HRH3ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL9048539 | 0.81 | HRH3 (0.53) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL9049511 | 0.80 | KCNH2 (0.59) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL10443267 | 0.80 | KCNH2 (0.54) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL10443393 | 0.80 | KCNH2 (0.54) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL10698327 | 0.80 | KCNH2 (0.54) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL10682867 | 0.79 | MEN1 (0.46) | KCNH2ALDH1A1KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391132-A1 | 5-Alkylquinolinone carboxylic acids | BAYER AG (DE) | 1990-10-10 | — | — | EP | disclosed |