Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | MAOB | P27338 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584535 | 0.90 | CYP1A2 (0.78) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL620074 | 0.89 | POLB (0.66) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL7008066 | 0.85 | HDAC3 (0.68) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL9491749 | 0.84 | HDAC3 (0.76) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL11476769 | 0.84 | CYP1A2 (0.70) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL3363697 | 0.83 | CYP1A2 (0.63) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL5656002 | 0.83 | SMN1; SMN2 (0.58) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL29262685 | 0.82 | CYP1A2 (0.68) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL6359975 | 0.82 | CYP1A2 (0.68) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL3506361 | 0.82 | MAOB (1.00) | CYP1A2TSHRNFKB1MAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| EP-3275440-B1 | NOVEL OXADIAZOLE DERIVATIVE AND PHARMACEUTICAL CONTAINING SAME | NAT CT GERIATRICS & GERONTOLOGY (JP) | 2022-05-04 | — | — | EP | disclosed |
| WO-2022053541-A1 | COMPOUNDS FOR USE AS APPETITE SUPPRESSANT | ERACAL THERAPEUTICS LTD. (CH) | 2022-03-17 | — | — | WO | disclosed |
| WO-2022053541-A1 | COMPOUNDS FOR USE AS APPETITE SUPPRESSANT | ERACAL THERAPEUTICS LTD. (CH) | 2022-03-17 | — | — | WO | disclosed |
| EP-3275440-A1 | NOVEL OXADIAZOLE DERIVATIVE AND PHARMACEUTICAL CONTAINING SAME | National Center for Geriatrics and Gerontology (JP) | 2018-01-31 | — | — | EP | disclosed |
| US-5238962-A | Administering an antidepressants | HOFFMANN-LA ROCHE INC. (US) | 1993-08-24 | — | — | US | disclosed |
| US-4874857-A | FIBER-REACTIVE DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-17 | — | — | US | disclosed |