Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23840194 | 0.84 | KCNMA1 (0.64) | KCNMA1RAB9ASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL24179294 | 0.78 | KCNMA1 (0.55) | KCNMA1RAB9ASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL20428912 | 0.75 | KCNMA1 (0.46) | KCNMA1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL20821940 | 0.75 | KCNMA1 (0.46) | KCNMA1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL25021088 | 0.74 | KCNMA1 (0.55) | KCNMA1RAB9ASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL8844809 | 0.74 | KCNMA1 (0.55) | KCNMA1RAB9ASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL22767716 | 0.73 | KCNMA1 (0.47) | KCNMA1RAB9ASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL24179215 | 0.71 | KCNMA1 (0.48) | KCNMA1RAB9ASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL4209963 | 0.70 | KCNMA1 (0.64) | KCNMA1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL80393 | 0.70 | KCNMA1 (1.00) | KCNMA1RAB9ASMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254552-A | Cognition activators, psychological disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-10-19 | — | — | US | disclosed |