Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1718737 | 0.86 | — | — | |
| SCHEMBL29263941 | 0.86 | HCAR2 (0.55) | HCAR2KEAP1NFE2L2CA12CA1 | |
| SCHEMBL1718738 | 0.86 | — | — | |
| SCHEMBL26696282 | 0.82 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2CA12CA1 | |
| SCHEMBL38250 | 0.82 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2CA12CA1 | |
| SCHEMBL38251 | 0.82 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2CA12CA1 | |
| SCHEMBL9585591 | 0.80 | CHRM2 (0.30) | — | |
| SCHEMBL7290177 | 0.80 | HCAR2 (0.44) | HCAR2CA12CA1CA2CA7 | |
| SCHEMBL7290180 | 0.80 | HCAR2 (0.44) | HCAR2CA12CA1CA2CA7 | |
| SCHEMBL9586721 | 0.80 | HCAR2 (0.44) | HCAR2CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5221753-A | PREPARATION OF 1-(4-TETRAHYDROPYRANYL)- OR 1-(4-TETRAHYDROTHIOPYRANYL)PROP-1-EN-3-ONES | BASF AKTIENGESELLSCHAFT (DE) | 1993-06-22 | — | — | US | disclosed |