Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 5/20 | 0.77 |
| ▸ | MAOB | P27338 | 7/20 | 0.75 |
| ▸ | MAOA | P21397 | 4/20 | 0.75 |
| ▸ | RXRA | P19793 | 2/20 | 0.62 |
| ▸ | RXRB | P28702 | 2/20 | 0.62 |
| ▸ | RXRG | P48443 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13802461 | 0.87 | NR4A2 (1.00) | NR4A2MAOBMAOARXRARXRB | |
| SCHEMBL29784229 | 0.87 | NR4A2 (1.00) | NR4A2MAOBMAOARXRARXRB | |
| SCHEMBL8694329 | 0.86 | MAOB (1.00) | NR4A2MAOBMAOARXRARXRB | |
| SCHEMBL15452539 | 0.86 | NR4A2 (0.77) | NR4A2MAOBMAOARXRARXRB | |
| SCHEMBL9586273 | 0.85 | NR4A2 (0.77) | NR4A2MAOBMRGPRX4 | |
| SCHEMBL9587641 | 0.83 | MAOB (0.76) | NR4A2MAOBMAOARXRARXRB | |
| SCHEMBL9586301 | 0.81 | NR4A2 (0.74) | NR4A2MAOBMAOARXRARXRB | |
| SCHEMBL9585749 | 0.81 | FFAR1 (0.60) | NR4A2MAOBMAOAMRGPRX4 | |
| SCHEMBL6951279 | 0.79 | NR4A2 (0.70) | NR4A2MAOBMAOARXRARXRB | |
| SCHEMBL6951282 | 0.79 | NR4A2 (0.70) | NR4A2MAOBMAOARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204482-A | Ethylenediamine monoamide heteroaryl derivatives | HOFFMAN-LAROCHE INC. (US) | 1993-04-20 | — | — | US | disclosed |
| US-5011849-A | Monoamine oxidase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 1991-04-30 | — | — | US | disclosed |