Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 7/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587439 | 0.91 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10GLAATM | |
| SCHEMBL9585879 | 0.86 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10GLAATM | |
| SCHEMBL30660078 | 0.86 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10AGTR1AGTR2 | |
| SCHEMBL3982628 | 0.86 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10AGTR1AGTR2 | |
| SCHEMBL9587150 | 0.85 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10GLAATM | |
| SCHEMBL9587493 | 0.83 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10GLAATM | |
| SCHEMBL9586006 | 0.82 | ALDH1A1 (0.38) | ALDH1A1KDM4EHSD17B10GLAATM | |
| SCHEMBL9587158 | 0.82 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10GLAATM | |
| SCHEMBL9586859 | 0.82 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10GLAATM | |
| SCHEMBL9588421 | 0.81 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018030-A1 | BENZIMIDAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-16 | — | — | WO | disclosed |