SCHEMBL9586509

SCHEMBL9586509

C(=C(c1ccccc1)c1ccccc1)n1ccnc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 8/20 0.43
CYP11B2 P19099 5/20 0.43
CYP3A4 P08684 2/20 0.41
TDP1 Q9NUW8 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
USP2 O75604 1/20 0.39
LMNA P02545 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
CYP11B1 P15538 3/20 0.38
TBXAS1 P24557 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP1A2 P05177 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
QPCT Q16769 1/20 0.38
CYP4Z1 Q86W10 1/20 0.38
QPCTL Q9NXS2 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9586788 0.98 CYP19A1 (0.42) CYP19A1CYP11B2CYP3A4TDP1MEN1
SCHEMBL9586794 0.82 NOTUM (0.44) CYP19A1CYP11B2CYP11B1TSHRIDO1
Hydrochloric Acid SCHEMBL9588288 0.81 NOTUM (0.43) CYP19A1CYP11B2CYP11B1TSHRIDO1
SCHEMBL10685566 0.78 TBXAS1 (0.56) CYP19A1TBXAS1POLB
SCHEMBL10685561 0.78 TBXAS1 (0.56) CYP19A1TBXAS1POLB
SCHEMBL9783192 0.77 CYP19A1 (0.37) CYP19A1CYP11B2CYP3A4TDP1MEN1
SCHEMBL9783446 0.77 CYP19A1 (0.37) CYP19A1CYP11B2CYP3A4TDP1MEN1
SCHEMBL11383428 0.77 CYP19A1 (0.42) CYP19A1CYP11B2CYP3A4TDP1MEN1
SCHEMBL11383413 0.77 CYP19A1 (0.42) CYP19A1CYP11B2CYP3A4TDP1MEN1
SCHEMBL10463399 0.76 TBXAS1 (0.57) CYP19A1CYP11B2CYP11B1TBXAS1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115246848-A Zero/negative thermal quenching near-infrared photoluminescence material and preparation method and application thereof 常州大学 2022-10-28 CN disclosed
CN-114276286-A Method for preparing N, N-disubstituted-alpha, beta-unsaturated enamine from arone and secondary nitrogen compound 长沙资材科技有限公司 2022-04-05 CN disclosed
US-5216007-A Fungicides ROHM AND HAAS COMPANY (US) 1993-06-01 US disclosed
EP-0076628-A2 Novel substituted imidazoles and triazoles, fungicidal compositions containing them and the use of the novel compounds for combating fungi ROHM AND HAAS COMPANY (US) 1983-04-13 EP disclosed