Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 5/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 5/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | IAPP | P10997 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.44 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404970 | 0.90 | ALOX15 (0.61) | ALOX15TRPV1MEN1KMT2ACYP2D6 | |
| SCHEMBL9404940 | 0.86 | ALOX15 (0.67) | ALOX15CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL9404808 | 0.85 | ALOX15 (0.65) | ALOX15CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL9404864 | 0.82 | ALOX15 (0.64) | ALOX15TRPV1 | |
| SCHEMBL9404934 | 0.76 | ALOX15 (0.59) | ALOX15TRPV1MEN1KMT2ALTA4H | |
| SCHEMBL9404953 | 0.76 | ALOX15 (0.59) | ALOX15TRPV1MEN1KMT2A | |
| SCHEMBL5822064 | 0.76 | KDM4E (0.51) | ALOX15MEN1KMT2A | |
| SCHEMBL15548241 | 0.74 | ALOX15 (0.68) | ALOX15TRPV1MEN1KMT2AIAPP | |
| SCHEMBL9404987 | 0.74 | ALOX15 (0.63) | ALOX15CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL15548000 | 0.73 | ALOX15 (0.70) | ALOX15CYP3A4CYP2C8CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246949-A | And lactic acid esters, treatment of hypotension and cardiac circulatory insufficiency | SANSHO CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |