Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | PRNP | P04156 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587127 | 0.77 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2GAALMNA | |
| SCHEMBL657973 | 0.74 | KMT2A (0.38) | MEN1KMT2ASMN1; SMN2GAALMNA | |
| SCHEMBL313449 | 0.73 | SMN1; SMN2 (0.56) | MEN1KMT2ASMN1; SMN2GAALMNA | |
| SCHEMBL5929583 | 0.73 | SMN1; SMN2 (0.56) | MEN1KMT2ASMN1; SMN2GAALMNA | |
| SCHEMBL1077616 | 0.72 | SMN1; SMN2 (0.55) | MEN1KMT2ASMN1; SMN2GAALMNA | |
| SCHEMBL1051991 | 0.72 | SMN1; SMN2 (0.55) | MEN1KMT2ASMN1; SMN2GAALMNA | |
| Hydrochloric Acid SCHEMBL5742023 | 0.71 | SMN1; SMN2 (0.53) | MEN1KMT2ASMN1; SMN2GAALMNA | |
| Hydrochloric Acid SCHEMBL7321879 | 0.71 | SMN1; SMN2 (0.53) | MEN1KMT2ASMN1; SMN2GAALMNA | |
| SCHEMBL9097352 | 0.71 | GAA (0.39) | MEN1KMT2ASMN1; SMN2GAALMNA | |
| SCHEMBL7548098 | 0.71 | SMN1; SMN2 (0.47) | MEN1KMT2ASMN1; SMN2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262430-A | Antidiabetic agent lowers blood glucose in mammals in type 2 non insulin dependent diabetes | NOVO NORDISK A/S (DK) | 1993-11-16 | — | — | US | disclosed |