Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7550096 | 0.76 | MTNR1A (0.46) | GAAMEN1KMT2ASMN1; SMN2FGFR2 | |
| SCHEMBL9587136 | 0.71 | MEN1 (0.44) | GAAMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL5929583 | 0.70 | SMN1; SMN2 (0.56) | GAAMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL313449 | 0.70 | SMN1; SMN2 (0.56) | GAAMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL9097726 | 0.70 | RAB9A (0.47) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL9587127 | 0.69 | MEN1 (0.46) | GAAMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7548098 | 0.67 | SMN1; SMN2 (0.47) | GAAMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL2300693 | 0.67 | MEN1 (0.40) | GAAMEN1KMT2ASMN1; SMN2FGFR2 | |
| SCHEMBL1077616 | 0.67 | SMN1; SMN2 (0.55) | GAAMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1051991 | 0.67 | SMN1; SMN2 (0.55) | GAAMEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482108-B1 | SUBSTITUTED 2-IMIDAZOLINES AND PREPARATION AND USE THEREOF | NOVO NORDISK AS (DK) | 1996-03-20 | — | — | EP | disclosed |
| US-5262430-A | Antidiabetic agent lowers blood glucose in mammals in type 2 non insulin dependent diabetes | NOVO NORDISK A/S (DK) | 1993-11-16 | — | — | US | disclosed |