Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | PTPRA | P18433 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27368380 | 0.91 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9ALMNAPGR | |
| SCHEMBL8191017 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9ALMNAPARP10 | |
| SCHEMBL29094856 | 0.83 | LPAR1 (0.50) | MAPTALDH1A1TSHRCYP3A4 | |
| SCHEMBL30753585 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ALMNAPARP10 | |
| SCHEMBL12320823 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ALMNAPARP10 | |
| SCHEMBL4012537 | 0.81 | NPC1 (0.56) | SMN1; SMN2NPC1RAB9ALMNAPARP10 | |
| SCHEMBL26617154 | 0.81 | NPC1 (0.56) | SMN1; SMN2NPC1RAB9ALMNAPARP10 | |
| SCHEMBL20509994 | 0.80 | SMN1; SMN2 (0.63) | SMN1; SMN2NPC1RAB9ALMNAPARP10 | |
| SCHEMBL20224957 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9ALMNACYP1A2 | |
| SCHEMBL6646352 | 0.80 | CYP4F2 (0.56) | SMN1; SMN2LMNAMAPTCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5331142-A | — | — | None | — | — | JP | disclosed |
| JP-H05331142-A | NEW AZELAIC ACID PYRIDYLALKYL DIESTER DERIVATIVE AND EXTERNAL PREPARATION FOR SKIN CONTAINING THE SAME | SHISEIDO CO LTD | 1993-12-14 | — | — | JP | disclosed |