Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587205 | 0.91 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9ALMNAHPGD | |
| SCHEMBL29094856 | 0.89 | LPAR1 (0.50) | CNR2HSD17B10TDP1ALDH1A1TSHR | |
| SCHEMBL8191017 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9ALMNAHPGD | |
| Hydrochloric Acid SCHEMBL10659395 | 0.83 | DGKA (0.55) | SMN1; SMN2NPC1RAB9ALMNATLR2 | |
| SCHEMBL12320823 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ALMNACNR2 | |
| SCHEMBL30753585 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ALMNACNR2 | |
| Butane SCHEMBL6637948 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9ALMNACNR2 | |
| SCHEMBL2964336 | 0.79 | CYP4F2 (0.57) | SMN1; SMN2LMNATLR2ALDH1A1 | |
| SCHEMBL11238689 | 0.79 | NPC1 (0.43) | SMN1; SMN2NPC1RAB9ALMNACNR2 | |
| SCHEMBL11236124 | 0.79 | NPC1 (0.43) | SMN1; SMN2NPC1RAB9ALMNACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067429-A | The 4-substituted alkyl carbapenem antibiotics | BRISTOL MYERS SQUIBB CO (US) | 1992-12-30 | — | — | CN | disclosed |