Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31688118 | 0.86 | GRM5 (0.47) | CCR1CCR8NOS3NOS2ALDH1A1 | |
| SCHEMBL5348383 | 0.86 | CCR1 (0.39) | CCR1CCR8NOS3NOS2ALDH1A1 | |
| SCHEMBL15004387 | 0.86 | GRM5 (0.47) | CCR1CCR8NOS3NOS2ALDH1A1 | |
| SCHEMBL77262 | 0.85 | CCR1 (0.50) | CCR1CCR8NOS3NOS2ALDH1A1 | |
| SCHEMBL29380771 | 0.85 | CCR1 (0.50) | CCR1CCR8NOS3NOS2ALDH1A1 | |
| SCHEMBL13821747 | 0.85 | CCR1 (0.50) | CCR1CCR8NOS3NOS2ALDH1A1 | |
| SCHEMBL25458041 | 0.83 | CCR1 (0.48) | CCR1CCR8NOS3NOS2ALDH1A1 | |
| SCHEMBL20031356 | 0.81 | CCR1 (0.46) | CCR1CCR8NOS3NOS2ALDH1A1 | |
| SCHEMBL20909878 | 0.81 | CCR1 (0.46) | CCR1CCR8NOS3NOS2ALDH1A1 | |
| SCHEMBL20892192 | 0.81 | CCR1 (0.46) | CCR1CCR8NOS3NOS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101981043-B | Metal complexes | MERCK PATENT GMBH | 2014-11-05 | — | — | CN | disclosed |
| US-8617723-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2013-12-31 | — | — | US | disclosed |
| US-20110012100-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110012100-A1 | METAL COMPLEXES | AP1M1, AP3M1, SOD1 | CCR1 1608/4885CCR8 3259/4885NOS3 2431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.