Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 3/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587160 | 0.92 | NPC1 (0.41) | NPC1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL9587746 | 0.90 | NPC1 (0.40) | NPC1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL9588753 | 0.89 | NPC1 (0.39) | NPC1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL9586735 | 0.85 | ALDH1A1 (0.38) | NPC1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL9597160 | 0.85 | NPC1 (0.40) | NPC1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL9587498 | 0.85 | ALDH1A1 (0.38) | NPC1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL9587393 | 0.83 | ALDH1A1 (0.39) | NPC1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL9585885 | 0.83 | ALDH1A1 (0.39) | NPC1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL9587365 | 0.82 | ALDH1A1 (0.38) | NPC1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL9587003 | 0.79 | FNTA (0.40) | NPC1MAPTALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018030-A1 | BENZIMIDAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-16 | — | — | WO | disclosed |