SCHEMBL9587718

SCHEMBL9587718

CNC(C(F)(F)F)(C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18487501 0.79
SCHEMBL17092891 0.69 LMNA (0.38) LMNA
SCHEMBL5145386 0.69 LMNA (0.38) LMNA
SCHEMBL5145567 0.69 LMNA (0.38) LMNA
SCHEMBL27639115 0.69 LMNA (0.38) LMNA
SCHEMBL5146900 0.69 LMNA (0.38) LMNA
SCHEMBL5145678 0.69 LMNA (0.38) LMNA
SCHEMBL7050453 0.69 LMNA (0.38) LMNA
Perflubutane SCHEMBL9051673 0.66 LMNA (0.54) LMNA
Perflubutane SCHEMBL111514 0.66 LMNA (0.54) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5214214-A Blood substitute THE GREEN CROSS CORPORATION (JP) 1993-05-25 US disclosed
US-4943595-A PERFLUOROALKYL ETHERS, BLOOD SUBSTITUTES THE GREEN CROSS CORPORATION (JP) 1990-07-24 US disclosed
EP-0077114-B1 PERFLUOROCHEMICALS, PROCESS FOR PREPARING THE SAME AND THEIR USE AS BLOOD SUBSTITUTES GREEN CROSS CORPORATION (JP) 1987-12-02 EP disclosed
EP-0077114-A1 Perfluorochemicals, process for preparing the same and their use as blood substitutes GREEN CROSS CORPORATION (JP) 1983-04-20 EP disclosed