Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 5/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.40 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586382 | 0.91 | CYP1A2 (0.42) | CNR1CYP1A2CYP3A4THPOALPL | |
| Hydrochloric Acid SCHEMBL9586015 | 0.87 | PMP22 (0.56) | CNR1CYP1A2CYP3A4THPOALPL | |
| SCHEMBL9586770 | 0.85 | CYP1A2 (0.44) | CYP1A2CYP3A4THPOLMNAPMP22 | |
| SCHEMBL9586508 | 0.83 | CYP1A2 (0.48) | CNR1CYP1A2CYP3A4THPOLMNA | |
| SCHEMBL10432812 | 0.82 | TMEM97 (0.40) | CNR1CYP1A2CYP3A4THPOALPL | |
| SCHEMBL9586228 | 0.81 | CYP1A2 (0.45) | CYP1A2CYP3A4THPOLMNAPMP22 | |
| SCHEMBL9587616 | 0.81 | CYP1A2 (0.58) | CYP1A2CYP3A4THPOLMNAPMP22 | |
| SCHEMBL4380087 | 0.81 | KDM4E (0.51) | ALPLSHMT1SHMT2GRM1GRM4 | |
| SCHEMBL9586100 | 0.80 | CYP1A2 (0.48) | CNR1CYP1A2CYP3A4THPOLMNA | |
| SCHEMBL9586973 | 0.80 | CYP1A2 (0.51) | CYP1A2CYP3A4THPOLMNAPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204482-A | Ethylenediamine monoamide heteroaryl derivatives | HOFFMAN-LAROCHE INC. (US) | 1993-04-20 | — | — | US | disclosed |
| US-5011849-A | Monoamine oxidase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 1991-04-30 | — | — | US | disclosed |