Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 14/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803490 | 0.87 | CYP11B1 (0.43) | CYP11B1CYP11B2ENPP2SIRT2KMT2A | |
| SCHEMBL1039275 | 0.84 | CYP11B1 (0.41) | CYP11B1CYP11B2ENPP2SIRT2KMT2A | |
| SCHEMBL4007072 | 0.83 | TAAR1 (0.40) | CYP11B1CYP11B2ENPP2SIRT2 | |
| SCHEMBL9587597 | 0.83 | SIRT2 (0.38) | CYP11B1CYP11B2ENPP2SIRT2 | |
| SCHEMBL4025463 | 0.81 | CYP11B1 (0.39) | CYP11B1CYP11B2ENPP2SIRT2KMT2A | |
| SCHEMBL14290021 | 0.81 | SIRT2 (0.37) | CYP11B1CYP11B2ENPP2SIRT2 | |
| SCHEMBL8497835 | 0.80 | CYP11B1 (0.38) | CYP11B1CYP11B2ENPP2SIRT2KMT2A | |
| SCHEMBL7451968 | 0.80 | CYP11B1 (0.38) | CYP11B1CYP11B2ENPP2SIRT2 | |
| SCHEMBL4002334 | 0.80 | CYP11B1 (0.38) | CYP11B1CYP11B2ENPP2SIRT2CYP3A4 | |
| SCHEMBL9073618 | 0.80 | CYP11B1 (0.38) | CYP11B1CYP11B2ENPP2SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256780-A | Serotonin antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-26 | — | — | US | disclosed |