Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | GRK6 | P43250 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9590145 | 0.90 | TYMS (0.37) | PTGER3TYMSALOX5TEKSIRT2 | |
| SCHEMBL9589264 | 0.89 | PNP (0.32) | TYMSMAOB | |
| SCHEMBL9589737 | 0.80 | PTGER3 (0.34) | MAPK8MAPK9MAPK10PTGER3GSTP1 | |
| SCHEMBL9590686 | 0.79 | TYMS (0.42) | TYMSSIRT2SIRT1MAOB | |
| SCHEMBL9587719 | 0.78 | TYMS (0.35) | TYMSMAOB | |
| SCHEMBL9588467 | 0.78 | MEN1 (0.39) | — | |
| SCHEMBL9251638 | 0.75 | PTGER3 (0.46) | PTGER3GSTP1 | |
| SCHEMBL9374084 | 0.74 | KDR (0.35) | MAPK8MAPK9MAOBTUBB4ATUBB | |
| SCHEMBL9374095 | 0.74 | KDR (0.35) | MAPK8MAPK9MAOBTUBB4ATUBB | |
| SCHEMBL9588163 | 0.73 | MIF (0.37) | PTGER3ALOX5MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993007137-A1 | PYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITHKLINE BEECHAM PLC (GB) | 1993-04-15 | — | — | WO | disclosed |