Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 9/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | PKN1 | Q16512 | 3/20 | 0.34 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 3/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9589444 | 0.90 | PARP1 (0.37) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9590755 | 0.88 | PARP1 (0.35) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9589820 | 0.86 | PNP (0.37) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9588138 | 0.83 | PARP1 (0.36) | GRIN2BPARP1PKN1PKN2CYP1A2 | |
| SCHEMBL9590336 | 0.82 | PARP1 (0.35) | GRIN2BPARP1PKN1PKN2CYP1A2 | |
| SCHEMBL9592001 | 0.81 | GRIN2B (0.42) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9590174 | 0.81 | PARP1 (0.35) | PARP1PKN1PKN2DHODHPLK4 | |
| SCHEMBL9589858 | 0.79 | CHRM1 (0.39) | GRIN2BPARP1CYP1A2CYP2D6DHODH | |
| SCHEMBL9589401 | 0.79 | PARP1 (0.36) | PARP1PKN1PKN2DHODHPLK4 | |
| SCHEMBL9587918 | 0.78 | PGK1 (0.33) | GRIN2BPGK1PGK2MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216003-A | Antihypoxic, antiischemic agents | G. D. SEARLE & CO. (US) | 1993-06-01 | — | — | US | disclosed |