Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 5/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588436 | 0.97 | AR (0.50) | ARMAPK14CETPPTGES2SLC6A2 | |
| SCHEMBL9588245 | 0.97 | AR (0.49) | ARMAPK14CETPPTGES2SLC6A2 | |
| SCHEMBL9588339 | 0.95 | AR (0.50) | ARMAPK14CETPSLC6A2SLC6A4 | |
| SCHEMBL9588248 | 0.92 | AR (0.48) | ARMAPK14CETPSLC6A2SLC6A4 | |
| SCHEMBL9589204 | 0.89 | SLC6A2 (0.53) | ARSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL9589491 | 0.87 | SLC6A2 (0.54) | ARSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL9589671 | 0.85 | AR (0.53) | ARMAPK14MEN1MAPTKMT2A | |
| SCHEMBL9589145 | 0.84 | SLC6A2 (0.51) | ARSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL9588301 | 0.84 | TTR (0.53) | ARMEN1MAPTKMT2AMITF | |
| SCHEMBL9588167 | 0.82 | LTA4H (0.53) | MAPK14CETPMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5219477-A | Containing organometallic salts and inorganic metal borates; fromo reactinmetal hydroxide with phenols or aromatic carboxylic acid | THE DOW CHEMICAL COMPANY (US) | 1993-06-15 | — | — | US | claimed |
| US-5219477-A | Containing organometallic salts and inorganic metal borates; fromo reactinmetal hydroxide with phenols or aromatic carboxylic acid | THE DOW CHEMICAL COMPANY (US) | 1993-06-15 | — | — | US | disclosed |