Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.61 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588289 | 1.00 | CHRM2 (0.61) | CHRM2CHRM5CHRM1CYP1A2CYP2D6 | |
| SCHEMBL12043330 | 0.82 | CHRM1 (0.69) | CHRM2CHRM5CHRM1CHRM4CHRM3 | |
| Hydrochloric Acid SCHEMBL9266187 | 0.81 | CHRM1 (0.67) | CHRM2CHRM5CHRM1CHRM4CHRM3 | |
| Hydrochloric Acid SCHEMBL9266191 | 0.81 | CHRM1 (0.67) | CHRM2CHRM5CHRM1CHRM4CHRM3 | |
| Dimethylamine SCHEMBL9629555 | 0.78 | CHRM1 (0.63) | CHRM2CHRM5CHRM1CHRM4CHRM3 | |
| Hydrochloric Acid SCHEMBL9262308 | 0.77 | CHRM2 (0.61) | CHRM2CHRM5CHRM1CHRM4CHRM3 | |
| Hydrochloric Acid SCHEMBL9262305 | 0.77 | CHRM2 (0.61) | CHRM2CHRM5CHRM1CHRM4CHRM3 | |
| Milameline SCHEMBL195143 | 0.77 | CHRM2 (1.00) | CHRM2CHRM5CHRM1CHRM4CHRM3 | |
| Milameline SCHEMBL8730172 | 0.77 | CHRM2 (1.00) | CHRM2CHRM5CHRM1CHRM4CHRM3 | |
| Milameline SCHEMBL5819625 | 0.75 | CHRM2 (0.97) | CHRM2CHRM5CHRM1CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5219872-A | Treating Alzheimer*s disease, memory disorders | ROUSSEL UCLAF (FR) | 1993-06-15 | — | — | US | disclosed |