Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.63 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12043330 | 0.95 | CHRM1 (0.69) | CHRM1CHRM2CHRM5LMNACHRM4 | |
| Hydrochloric Acid SCHEMBL9266191 | 0.94 | CHRM1 (0.67) | CHRM1CHRM2CHRM5LMNACHRM4 | |
| Hydrochloric Acid SCHEMBL9266187 | 0.94 | CHRM1 (0.67) | CHRM1CHRM2CHRM5LMNACHRM4 | |
| Hydrochloric Acid SCHEMBL9262305 | 0.81 | CHRM2 (0.61) | CHRM1CHRM2CHRM5LMNACHRM4 | |
| Hydrochloric Acid SCHEMBL9262308 | 0.81 | CHRM2 (0.61) | CHRM1CHRM2CHRM5LMNACHRM4 | |
| SCHEMBL9588290 | 0.78 | CHRM2 (0.61) | CHRM1CHRM2CHRM5LMNACHRM4 | |
| SCHEMBL9588289 | 0.78 | CHRM2 (0.61) | CHRM1CHRM2CHRM5LMNACHRM4 | |
| Milameline SCHEMBL8730172 | 0.78 | CHRM2 (1.00) | CHRM1CHRM2CHRM5LMNACHRM4 | |
| Milameline SCHEMBL195143 | 0.78 | CHRM2 (1.00) | CHRM1CHRM2CHRM5LMNACHRM4 | |
| Milameline SCHEMBL8730187 | 0.76 | CHRM2 (0.97) | CHRM1CHRM2CHRM5LMNACHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239445-B1 | 1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXALDEHYDE OXIME DERIVATIVES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE AS MEDICINES | ROUSSEL-UCLAF (FR) | 1992-05-13 | — | — | EP | disclosed |
| EP-0239445-A2 | 1,2,5,6-Tetrahydropyridine-3-carboxaldehyde oxime derivatives, process for their preparation, compositions containing them and their use as medicines | ROUSSEL-UCLAF (FR) | 1987-09-30 | — | — | EP | disclosed |