Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9589803 | 0.84 | KDM4E (0.58) | KDM4EALDH1A1NPSR1MAPK1TSHR | |
| SCHEMBL9647620 | 0.84 | KDM4E (0.58) | KDM4EALDH1A1NPSR1MAPK1TSHR | |
| SCHEMBL9590027 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1NPSR1TSHRHPGD | |
| SCHEMBL9589866 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1NPSR1HTR6MAPK1 | |
| SCHEMBL9270572 | 0.81 | KDM4E (0.54) | KDM4EALDH1A1NPSR1TSHRHPGD | |
| SCHEMBL1148794 | 0.80 | MAPK1 (0.52) | KDM4EALDH1A1NPSR1MAPK1HPGD | |
| SCHEMBL9592310 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1 | |
| SCHEMBL9644857 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1NPSR1TSHRHPGD | |
| SCHEMBL9645974 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1NPSR1TSHRHPGD | |
| SCHEMBL9589962 | 0.79 | KDM4E (0.52) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190960-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1993-03-02 | — | — | US | disclosed |
| US-5155116-A | Analgesics devoid of antiinflammatory activity | ADIR ET COMPAGNIE (FR) | 1992-10-13 | — | — | US | disclosed |