Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644857 | 1.00 | KDM4E (0.53) | KDM4EALDH1A1NPSR1TSHRUSP2 | |
| SCHEMBL9270572 | 0.99 | KDM4E (0.54) | KDM4EALDH1A1NPSR1TSHRUSP2 | |
| SCHEMBL9590027 | 0.94 | KDM4E (0.56) | KDM4EALDH1A1NPSR1TSHRUSP2 | |
| SCHEMBL9589803 | 0.88 | KDM4E (0.58) | KDM4EALDH1A1NPSR1TSHRUSP2 | |
| SCHEMBL1148794 | 0.81 | MAPK1 (0.52) | KDM4EALDH1A1NPSR1HPGDSMN1; SMN2 | |
| SCHEMBL9644908 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1 | |
| SCHEMBL9645830 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1 | |
| SCHEMBL9588299 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1NPSR1TSHRUSP2 | |
| SCHEMBL9647620 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1NPSR1TSHRUSP2 | |
| SCHEMBL9645855 | 0.78 | KDM4E (0.54) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084456-A | Analgesics | SCIENCE ET ORGANISATION (FR) | 1992-01-28 | — | — | US | disclosed |