Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9592026 | 0.81 | CYP2C19 (0.48) | NPSR1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL14066227 | 0.81 | MAPK1 (0.39) | NPSR1MAPTKDM4EPOLBCYP2C9 | |
| SCHEMBL9589566 | 0.80 | ERAP2 (0.39) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL9590334 | 0.75 | MAPK1 (0.47) | KMT2AMEN1ALDH1A1GAALMNA | |
| SCHEMBL24967427 | 0.74 | MAPK1 (0.48) | MAPTKMT2AMEN1KDM4ECYP2C9 | |
| SCHEMBL24966942 | 0.74 | MAPK1 (0.62) | MAPTKMT2ATDP1MEN1CYP2C9 | |
| SCHEMBL15330975 | 0.72 | HSD17B10 (0.55) | HSD17B10NPSR1MAPTKMT2ATDP1 | |
| SCHEMBL13279340 | 0.72 | PTGS2 (0.44) | HSD17B10MAPTKDM4EPOLBCYP2C9 | |
| SCHEMBL4128009 | 0.72 | HSD17B10 (0.63) | HSD17B10NPSR1MAPTKMT2ATDP1 | |
| SCHEMBL1243976 | 0.72 | CNR2 (0.55) | MAPTKDM4EPOLBRAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242939-A | Hypotensive | WARNER-LAMBERT COMPANY (US) | 1993-09-07 | — | — | US | disclosed |
| WO-1992006081-A1 | ANILIDE DERIVATIVES WITH ANGIOTENSIN II ANTAGONIST PROPERTIES | WARNER-LAMBERT COMPANY (US) | 1992-04-16 | — | — | WO | disclosed |