Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.65 |
| ▸ | DRD3 | P35462 | 4/20 | 0.65 |
| ▸ | DRD4 | P21917 | 3/20 | 0.65 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | DRD1 | P21728 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA3 | P07451 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodopride SCHEMBL30607707 | 0.89 | DRD2 (0.80) | DRD2DRD3DRD4ADRA2BADRA2C | |
| Iodopride SCHEMBL9502371 | 0.89 | DRD2 (0.80) | DRD2DRD3DRD4ADRA2BADRA2C | |
| SCHEMBL9588023 | 0.89 | DRD2 (0.70) | DRD2DRD3DRD4ADRA2BADRA2C | |
| Iodopride SCHEMBL10579084 | 0.89 | DRD2 (0.80) | DRD2DRD3DRD4ADRA2BADRA2C | |
| SCHEMBL9590996 | 0.88 | DRD2 (0.80) | DRD2DRD3DRD4ADRA2BADRA2C | |
| SCHEMBL9588375 | 0.84 | DRD2 (0.57) | DRD2DRD3DRD4CYP2D6 | |
| SCHEMBL9253650 | 0.83 | DRD2 (0.58) | DRD2DRD3DRD4ADRA2BADRA2C | |
| SCHEMBL11904262 | 0.82 | DRD2 (0.68) | DRD2DRD3DRD4CA2DRD1 | |
| SCHEMBL11054916 | 0.80 | DRD2 (0.80) | DRD2DRD3DRD4ADRA2BADRA2C | |
| Epidepride SCHEMBL8961800 | 0.80 | DRD2 (0.81) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5186921-A | 3-methoxy-n(1-ethyl-2-pyrrolidinyl)methyl)naphthyl-2-carboxy amide compounds for imaging human brains; good retention stability | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1993-02-16 | — | — | US | claimed |