Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1065778 | 0.88 | DHFR (0.59) | DHFRGHSR | |
| SCHEMBL9586237 | 0.88 | DHFR (0.59) | DHFRGHSR | |
| SCHEMBL9587570 | 0.86 | DHFR (0.57) | DHFRGHSR | |
| SCHEMBL9587214 | 0.86 | DHFR (0.57) | DHFRGHSR | |
| SCHEMBL9586972 | 0.84 | DHFR (0.55) | DHFRGHSR | |
| SCHEMBL9587800 | 0.84 | DHFR (0.70) | DHFR | |
| SCHEMBL9586768 | 0.83 | DHFR (0.54) | DHFRGHSR | |
| SCHEMBL9587848 | 0.83 | DHFR (0.57) | DHFR | |
| SCHEMBL9587038 | 0.81 | DHFR (0.53) | DHFR | |
| SCHEMBL9587845 | 0.81 | DHFR (0.52) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013079-A1 | ANTIFOLATE QUINAZOLINES | AGOURON PHARMACEUTICALS, INC. (US) | 1993-07-08 | — | — | WO | disclosed |