Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.55 |
| ▸ | RELA | Q04206 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | ACR | P10323 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588652 | 1.00 | LMNA (0.56) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9592230 | 0.99 | LMNA (0.57) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9592218 | 0.99 | LMNA (0.57) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9590374 | 0.96 | LMNA (0.60) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9589913 | 0.96 | LMNA (0.60) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9590381 | 0.96 | LMNA (0.60) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9589923 | 0.96 | LMNA (0.60) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9590464 | 0.95 | LMNA (0.61) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9590469 | 0.95 | LMNA (0.61) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9590390 | 0.95 | LMNA (0.62) | LMNANPC1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5238600-A | IBIMETHYLENOXY CONTAINING LIQUID CRYSTAL COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 1993-08-24 | — | — | US | disclosed |