Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587879 | 0.90 | ADORA3 (0.46) | ADORA3ADORA1ADORA2AADORA2BCCNA2 | |
| Methyl Alcohol SCHEMBL9587418 | 0.89 | ADORA3 (0.46) | ADORA3ADORA1ADORA2AADORA2BCCNA2 | |
| SCHEMBL9587900 | 0.88 | ADORA3 (0.47) | ADORA3ADORA1ADORA2AADORA2BCCNA2 | |
| SCHEMBL9589210 | 0.88 | ADORA1 (0.45) | ADORA3ADORA1ADORA2AADORA2BCCNA2 | |
| SCHEMBL9587408 | 0.87 | ADORA3 (0.44) | ADORA3ADORA1ADORA2AADORA2BCCNA2 | |
| SCHEMBL9587640 | 0.85 | ADORA1 (0.44) | ADORA3ADORA1ADORA2AADORA2BCCNA2 | |
| SCHEMBL9587659 | 0.84 | CCNA2 (0.42) | ADORA3ADORA1ADORA2AADORA2BCCNA2 | |
| SCHEMBL9586410 | 0.84 | ADORA1 (0.44) | ADORA3ADORA1ADORA2AADORA2BCCNA2 | |
| SCHEMBL9589084 | 0.84 | NPC1 (0.44) | ADORA3ADORA1ADORA2AADORA2BCCNA2 | |
| SCHEMBL9588221 | 0.84 | ADORA1 (0.43) | ADORA3ADORA1ADORA2AADORA2BCCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185437-A | 6-substituted 2',3'-dideoxypurine nucleosides; treatment for human immunodeficiency virus and heptatis b virus | BURROUGHS WELLCOME CO. (US) | 1993-02-09 | — | — | US | disclosed |
| US-5068320-A | 2-amino-6-(cyclopropylamino)purine-9-β-D-2',3'-dideoxyribofuranoside and its pharmaceutically acceptable salts | BURROUGHS WELLCOME CO. (US) | 1991-11-26 | — | — | US | disclosed |