Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | OGT | O15294 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 3/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29578046 | 0.98 | HTT (0.61) | HTTHSD17B10OGTGRM5AURKA | |
| SCHEMBL340652 | 0.98 | HTT (0.61) | HTTHSD17B10OGTGRM5AURKA | |
| Hydrochloric Acid SCHEMBL30693613 | 0.96 | HTT (0.59) | HTTHSD17B10OGTGRM5AURKA | |
| SCHEMBL9588973 | 0.96 | HTT (0.59) | HTTHSD17B10OGTGRM5AURKA | |
| SCHEMBL1522777 | 0.76 | PARP1 (0.53) | HTTHSD17B10AURKAPARP1ALDH1A1 | |
| SCHEMBL19897476 | 0.76 | PARP1 (0.46) | HTTHSD17B10OGTGRM5AURKA | |
| SCHEMBL29422383 | 0.74 | HSD17B10 (1.00) | HTTHSD17B10AURKAPARP1KDM4E | |
| SCHEMBL778314 | 0.74 | HSD17B10 (1.00) | HTTHSD17B10AURKAPARP1KDM4E | |
| SCHEMBL341634 | 0.67 | NOS1 (0.37) | HTTHSD17B10OGTAURKAPARP1 | |
| SCHEMBL14358997 | 0.67 | PDE3B (0.44) | OGTGRM5PDE3BPDE3ASYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190960-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1993-03-02 | — | — | US | disclosed |
| US-5155116-A | Analgesics devoid of antiinflammatory activity | ADIR ET COMPAGNIE (FR) | 1992-10-13 | — | — | US | disclosed |
| US-5084456-A | Analgesics | SCIENCE ET ORGANISATION (FR) | 1992-01-28 | — | — | US | disclosed |