Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.43 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6442887 | 0.86 | KEAP1 (0.52) | TDP1RAB9AKEAP1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL6356557 | 0.79 | GAA (0.47) | TDP1RAB9AGPR52CYP1A2CYP3A4 | |
| SCHEMBL11304333 | 0.78 | TDP1 (0.62) | TDP1LMNARAB9AGPR52CYP1A2 | |
| SCHEMBL17010799 | 0.78 | KEAP1 (0.44) | TDP1RAB9AKEAP1ALDH1A1KMT2A | |
| SCHEMBL3988722 | 0.76 | ESR1 (0.48) | CYP2C19ALDH1A1FFAR1KDM4E | |
| SCHEMBL21042137 | 0.74 | FFAR1 (0.41) | TDP1RAB9AKEAP1ALDH1A1HPGD | |
| SCHEMBL1276188 | 0.73 | MAPT (0.55) | TDP1RAB9ASMN1; SMN2 | |
| SCHEMBL2025813 | 0.73 | TSHR (0.50) | TDP1RAB9AKEAP1ALDH1A1FFAR1 | |
| SCHEMBL9114210 | 0.73 | CYP1A2 (0.65) | TDP1LMNARAB9ACYP1A2CYP3A4 | |
| SCHEMBL25986973 | 0.71 | KDM4E (0.46) | TDP1LMNARAB9ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262420-A | Phenylalkylpyridines | IDEMITSU KOSAN CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0383950-A1 | PYRIDINE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENT CONTAINING SAME AS ACTIVE INGREDIENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-08-29 | — | — | EP | disclosed |